On a 14th century house-tower, belonging to Gaia da Camino, the Persico family built its palazzo. The facade, characterised by memorial stones, was added between 1496 and 1506. After 1596 it belonged to the historian Giorgio Piloni. It was extensively modified in the 1800’s. A devastating fire in 1933 left only the facade intact. It was reconstructed in 1941.